In this article, I revisit my marginalized and silent intellectual relationship with Gloria E. Anzaldúa’s work, my personal experiences as a Mexican immigrant woman in academia, and my incorporation and discussion of Anzaldúan theorizing in my qualitative research on incest in Mexican society. I examine the ways in which Anzaldúan theories and concepts inform the early stages of my sociological study of adults’ histories of intra-familial sexual experiences (mainly coercive and abusive) during childhood and adolescence. Some of these concepts include nepantla, conocimiento, spiritual activism, la facultad, and Coyolxauhqui. “Epistemologies of the wound” is a concept I use to identify the multidimensional state of consciousness I have discovered and explored at the core of the mutually interconnected intellectual, emotional, and spiritual processes I have experienced while conducting my in-depth individual interviews with my informants. My sample includes a total of 60 adult women and men with histories of coercive sexual experiences within the context of the family, and who live in four urbanized locations in Mexico (Ciudad Juárez, Guadalajara, Mexico City, and Monterrey). I offer my early reflections on the theoretical and methodological implications of Anzaldúan epistemologies for the sociological research of sensitive topics.